Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

Download FIRM

Citation

END Ovarian Hendrix Cluster Number 6 (144 genes) This page contains all miRNA mediated regulation and functional enrichment for END Ovarian Hendrix cluster number 6. Information about ovarian cancer can be found on Wikipedia, and further information about the "END Ovarian Hendrix" dataset can be found in Hendrix et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-29b hsa-mir-29c hsa-mir-29a hsa-mir-890 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001501 skeletal system development 15 GO:0001503 ossification 9 GO:0001568 blood vessel development 15 GO:0001655 urogenital system development 9 GO:0001822 kidney development 8 GO:0001944 vasculature development 15 GO:0007155 cell adhesion 34 GO:0007167 enzyme linked receptor protein signaling pathway 22 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 11 GO:0007179 transforming growth factor beta receptor signaling pathway 8 GO:0007275 multicellular organismal development 67 GO:0009653 anatomical structure morphogenesis 36 GO:0022610 biological adhesion 34 GO:0030154 cell differentiation 38 GO:0030198 extracellular matrix organization 9 GO:0030199 collagen fibril organization 5 GO:0031589 cell-substrate adhesion 9 GO:0032501 multicellular organismal process 80 GO:0032502 developmental process 68 GO:0043062 extracellular structure organization 10 GO:0048513 organ development 39 GO:0048731 system development 58 GO:0048856 anatomical structure development 61 GO:0051674 localization of cell 17 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-29b PITA GO:0001501 skeletal system development 6 15 144 18 0.0005146702 hsa-mir-29c PITA GO:0001501 skeletal system development 6 15 144 18 0.0005146702 hsa-mir-29a PITA GO:0001501 skeletal system development 6 15 144 18 0.0005146702 hsa-mir-890 TargetScan GO:0001501 skeletal system development 5 15 144 38 0.1687236 hsa-mir-29b PITA GO:0001503 ossification 2 9 144 18 0.08545954 hsa-mir-29c PITA GO:0001503 ossification 2 9 144 18 0.08545954 hsa-mir-29a PITA GO:0001503 ossification 2 9 144 18 0.08545954 hsa-mir-890 TargetScan GO:0001503 ossification 4 9 144 38 0.05455946 hsa-mir-29b PITA GO:0001568 blood vessel development 5 15 144 18 0.004097323 hsa-mir-29c PITA GO:0001568 blood vessel development 5 15 144 18 0.004097323 hsa-mir-29a PITA GO:0001568 blood vessel development 5 15 144 18 0.004097323 hsa-mir-890 TargetScan GO:0001568 blood vessel development 5 15 144 38 0.1687236 hsa-mir-29b PITA GO:0001655 urogenital system development 2 9 144 18 0.08545954 hsa-mir-29c PITA GO:0001655 urogenital system development 2 9 144 18 0.08545954 hsa-mir-29a PITA GO:0001655 urogenital system development 2 9 144 18 0.08545954 hsa-mir-890 TargetScan GO:0001655 urogenital system development 4 9 144 38 0.05455946 hsa-mir-29b PITA GO:0001822 kidney development 2 8 144 18 0.06189469 hsa-mir-29c PITA GO:0001822 kidney development 2 8 144 18 0.06189469 hsa-mir-29a PITA GO:0001822 kidney development 2 8 144 18 0.06189469 hsa-mir-890 TargetScan GO:0001822 kidney development 3 8 144 38 0.127662 hsa-mir-29b PITA GO:0001944 vasculature development 5 15 144 18 0.004097323 hsa-mir-29c PITA GO:0001944 vasculature development 5 15 144 18 0.004097323 hsa-mir-29a PITA GO:0001944 vasculature development 5 15 144 18 0.004097323 hsa-mir-890 TargetScan GO:0001944 vasculature development 5 15 144 38 0.1687236 hsa-mir-29b PITA GO:0007155 cell adhesion 5 34 144 18 0.2239202 hsa-mir-29c PITA GO:0007155 cell adhesion 5 34 144 18 0.2239202 hsa-mir-29a PITA GO:0007155 cell adhesion 5 34 144 18 0.2239202 hsa-mir-890 TargetScan GO:0007155 cell adhesion 8 34 144 38 0.5759836 hsa-mir-29b PITA GO:0007167 enzyme linked receptor protein signaling pathway 8 22 144 18 0.000184415 hsa-mir-29c PITA GO:0007167 enzyme linked receptor protein signaling pathway 8 22 144 18 0.000184415 hsa-mir-29a PITA GO:0007167 enzyme linked receptor protein signaling pathway 8 22 144 18 0.000184415 hsa-mir-890 TargetScan GO:0007167 enzyme linked receptor protein signaling pathway 6 22 144 38 0.3485349 hsa-mir-29b PITA GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 4 11 144 18 0.005034239 hsa-mir-29c PITA GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 4 11 144 18 0.005034239 hsa-mir-29a PITA GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 4 11 144 18 0.005034239 hsa-mir-890 TargetScan GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 4 11 144 38 0.1293301 hsa-mir-29b PITA GO:0007179 transforming growth factor beta receptor signaling pathway 4 8 144 18 0.0007812512 hsa-mir-29c PITA GO:0007179 transforming growth factor beta receptor signaling pathway 4 8 144 18 0.0007812512 hsa-mir-29a PITA GO:0007179 transforming growth factor beta receptor signaling pathway 4 8 144 18 0.0007812512 hsa-mir-890 TargetScan GO:0007179 transforming growth factor beta receptor signaling pathway 2 8 144 38 0.3549064 hsa-mir-29b PITA GO:0007275 multicellular organismal development 16 67 144 18 7.359681e-06 hsa-mir-29c PITA GO:0007275 multicellular organismal development 16 67 144 18 7.359681e-06 hsa-mir-29a PITA GO:0007275 multicellular organismal development 16 67 144 18 7.359681e-06 hsa-mir-890 TargetScan GO:0007275 multicellular organismal development 16 67 144 38 0.6719617 hsa-mir-29b PITA GO:0009653 anatomical structure morphogenesis 11 36 144 18 7.317707e-05 hsa-mir-29c PITA GO:0009653 anatomical structure morphogenesis 11 36 144 18 7.317707e-05 hsa-mir-29a PITA GO:0009653 anatomical structure morphogenesis 11 36 144 18 7.317707e-05 hsa-mir-890 TargetScan GO:0009653 anatomical structure morphogenesis 9 36 144 38 0.4930095 hsa-mir-29b PITA GO:0022610 biological adhesion 5 34 144 18 0.2239202 hsa-mir-29c PITA GO:0022610 biological adhesion 5 34 144 18 0.2239202 hsa-mir-29a PITA GO:0022610 biological adhesion 5 34 144 18 0.2239202 hsa-mir-890 TargetScan GO:0022610 biological adhesion 8 34 144 38 0.5759836 hsa-mir-29b PITA GO:0030154 cell differentiation 10 38 144 18 0.0009452345 hsa-mir-29c PITA GO:0030154 cell differentiation 10 38 144 18 0.0009452345 hsa-mir-29a PITA GO:0030154 cell differentiation 10 38 144 18 0.0009452345 hsa-mir-890 TargetScan GO:0030154 cell differentiation 11 38 144 38 0.2608697 hsa-mir-29b PITA GO:0030198 extracellular matrix organization 4 9 144 18 0.001619318 hsa-mir-29c PITA GO:0030198 extracellular matrix organization 4 9 144 18 0.001619318 hsa-mir-29a PITA GO:0030198 extracellular matrix organization 4 9 144 18 0.001619318 hsa-mir-890 TargetScan GO:0030198 extracellular matrix organization 3 9 144 38 0.186144 hsa-mir-29b PITA GO:0030199 collagen fibril organization 4 5 144 18 1.781257e-05 hsa-mir-29c PITA GO:0030199 collagen fibril organization 4 5 144 18 1.781257e-05 hsa-mir-29a PITA GO:0030199 collagen fibril organization 4 5 144 18 1.781257e-05 hsa-mir-890 TargetScan GO:0030199 collagen fibril organization 2 5 144 38 0.11491 hsa-mir-29b PITA GO:0031589 cell-substrate adhesion 1 9 144 18 0.312692 hsa-mir-29c PITA GO:0031589 cell-substrate adhesion 1 9 144 18 0.312692 hsa-mir-29a PITA GO:0031589 cell-substrate adhesion 1 9 144 18 0.312692 hsa-mir-890 TargetScan GO:0031589 cell-substrate adhesion 2 9 144 38 0.4392876 hsa-mir-29b PITA GO:0032501 multicellular organismal process 16 80 144 18 0.0001874552 hsa-mir-29c PITA GO:0032501 multicellular organismal process 16 80 144 18 0.0001874552 hsa-mir-29a PITA GO:0032501 multicellular organismal process 16 80 144 18 0.0001874552 hsa-mir-890 TargetScan GO:0032501 multicellular organismal process 18 80 144 38 0.8397812 hsa-mir-29b PITA GO:0032502 developmental process 17 68 144 18 3.485086e-07 hsa-mir-29c PITA GO:0032502 developmental process 17 68 144 18 3.485086e-07 hsa-mir-29a PITA GO:0032502 developmental process 17 68 144 18 3.485086e-07 hsa-mir-890 TargetScan GO:0032502 developmental process 17 68 144 38 0.566109 hsa-mir-29b PITA GO:0043062 extracellular structure organization 4 10 144 18 0.002982574 hsa-mir-29c PITA GO:0043062 extracellular structure organization 4 10 144 18 0.002982574 hsa-mir-29a PITA GO:0043062 extracellular structure organization 4 10 144 18 0.002982574 hsa-mir-890 TargetScan GO:0043062 extracellular structure organization 3 10 144 38 0.2517738 hsa-mir-29b PITA GO:0048513 organ development 12 39 144 18 2.356922e-05 hsa-mir-29c PITA GO:0048513 organ development 12 39 144 18 2.356922e-05 hsa-mir-29a PITA GO:0048513 organ development 12 39 144 18 2.356922e-05 hsa-mir-890 TargetScan GO:0048513 organ development 11 39 144 38 0.2998285 hsa-mir-29b PITA GO:0048731 system development 16 58 144 18 4.771962e-07 hsa-mir-29c PITA GO:0048731 system development 16 58 144 18 4.771962e-07 hsa-mir-29a PITA GO:0048731 system development 16 58 144 18 4.771962e-07 hsa-mir-890 TargetScan GO:0048731 system development 15 58 144 38 0.4677969 hsa-mir-29b PITA GO:0048856 anatomical structure development 17 61 144 18 3.590777e-08 hsa-mir-29c PITA GO:0048856 anatomical structure development 17 61 144 18 3.590777e-08 hsa-mir-29a PITA GO:0048856 anatomical structure development 17 61 144 18 3.590777e-08 hsa-mir-890 TargetScan GO:0048856 anatomical structure development 17 61 144 38 0.2947452 hsa-mir-29b PITA GO:0051674 localization of cell 4 17 144 18 0.04082387 hsa-mir-29c PITA GO:0051674 localization of cell 4 17 144 18 0.04082387 hsa-mir-29a PITA GO:0051674 localization of cell 4 17 144 18 0.04082387 hsa-mir-890 TargetScan GO:0051674 localization of cell 5 17 144 38 0.268955

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.